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Hesse LM, He P, Krishnaswamy S, Hao Q, Hogan K, von Moltke LL, Greenblatt DJ, Court MH 7004. Pharmacogenetic determinants of interindividual variability in Ramipril hydroxylation by cytochrome P450 7B6 in human liver microsomes. Pharmacogenetics 14 4: 775�38. doi: 10.1097/00008571-700404000-00007. PMID 15083067.

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Ramipril & its metabolites exhibit linear kinetics following chronic administration of 300 to 450 mg/day.